Blue Jays at Yankees Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 25

Its Friday, April 25 and the Blue Jays (12-13) are in Bronx to begin a series against the Yankees (15-10).

José Berríos is slated to take the mound for Toronto against Carlos Carrasco for New York.

The Yankees return home following a seven-game road trip. The Bronx Bombers went 4-3 for the week. Aaron Judge picked up hits in six of the seven games going 12-28 (.429) for the trip.

The Blue Jays Have lost five in a row including the last three in Houston. Toronto scored all of two runs in the three-game set against the Astros.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Blue Jays at Yankees

• Date: Friday, April 25, 2025
• Time: 7:05PM EST
• Site: Yankee Stadium
• City: Bronx, NY
• Network/Streaming: SN1, YES, MLBN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Blue Jays at the Yankees

The latest odds as of Friday:

• Moneyline: Blue Jays (+115), Yankees (-137)
• Spread:  Yankees -1.5
• Total: 10.0 runs

Probable starting pitchers for Blue Jays at Yankees

• Pitching matchup for April 25, 2025: José Berríos vs. Carlos Carrasco
  
  • Blue Jays: José Berríos (1-1, 5.02 ERA)
    Last outing: 4/19 vs. Seattle - 6IP, 3ER, 4H, 4BB, 3Ks
  • Yankees: Carlos Carrasco (2-1, 6.53 ERA)
    Last outing: 4/19 @ Tampa Bay - 4IP, 4ER, 6H, 2BB, 1K

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Blue Jays at Yankees

• The Blue Jays have lost their last 5 and failed to cover the Run Line in each
• The Under has cashed in the Blue Jays' last 3 games
• Vlad Guerrero Jr. was 1-12 in the 3-game series in Houston
• Antony Volpe is 4-27 (.148) in his last 7 games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Blue Jays and the Yankees

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday's game between the Blue Jays and the Yankees:

• Moneyline: NBC Sports Bet is recommending a play on the New York Yankees on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Toronto Blue Jays at +1.5.
• Total: NBC Sports Bet is recommending a play on the under on the Game Total of 10.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)