Giants at Phillies Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 15

Its Tuesday, April 15 and the Giants (12-4) are in Philadelphia to take on the Phillies (9-7).

Justin Verlander is slated to take the mound for San Francisco against Jesús Luzardo for Philadelphia.

The Giants smacked Philly last night winning the opener 10-4. Tyler Fitzgerald led the assault driving in three runs with a double, triple, and home run for San Francisco. Five Giants' pitchers combined to strike out 13 Phillies.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Giants at Phillies

• Date: Tuesday, April 15, 2025
• Time: 6:45PM EST
• Site: Citizens Bank Park
• City: Philadelphia, PA
• Network/Streaming: NBCSBA, NBCSP+

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Giants at the Phillies

The latest odds as of Tuesday:

• Moneyline: Giants (+124), Phillies (-148)
• Spread:  Phillies -1.5
• Total: 8.0 runs

Probable starting pitchers for Giants at Phillies

• Pitching matchup for April 15, 2025: Justin Verlander vs. Jesús Luzardo
  
  • Giants: Justin Verlander (0-0, 6.92 ERA)
    Last outing: 4/9 vs. Cincinnati - 5.2IP, 5ER, 5H, 3BB, 9Ks
  • Phillies: Jesús Luzardo (2-0, 1.50 ERA)
    Last outing: 4/10 at Atlanta - 6IP, 1ER, 6H, 1BB, 6Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Giants at Phillies

• The Giants have won 4 of their last 5 games
• Giants' games have cashed to the OVER in 11 of 16 games
• Phillies' games have cashed to the UNDER in 11 of 16 games
• Jesus Luzardo has 14Ks in his last 2 starts (13IP)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Giants and the Phillies

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Tuesday's game between the Giants and the Phillies:

• Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the San Francisco Giants at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)