Thursday Night Football: Isaac Guerendo, Nick Bosa, Dre Greenlaw are active for 49ers

The 49ers will have defensive lineman Nick Bosa, linebacker Dre Greenlaw and running back Isaac Guerendo for Thursday Night Football. All three are active after receiving questionable designations.

Bosa returns after missing three games with hip and oblique injuries he aggravated in Week 11 against the Seahawks, while Greenlaw will make his 2024 debut after working his way back from an Achilles tear in Super Bowl LVIII.

Guerendo sprained his foot in last week's game.

The 49ers ruled out left tackle Trent Williams (ankle), quarterback Joshua Dobbs, defensive lineman Khalil Davis (knee), safety Malik Mustapha (chest/shoulder), running back Israel Abanikanda and cornerback Rock Ya-Sin. Dobbs will serve as the emergency third quarterback.

The Rams' inactives are quarterback Stetson Bennett, cornerback Cobie Durant (chest), running back Cody Schrader, outside linebacker Brennan Jackson, offensive lineman Dylan McMahon and offensive lineman Warren McClendon Jr.

Cornerback Emmanuel Forbes is active and expected to make his Rams debut.